* == Upset.
| Seed | Score | Team | Record | Seed | Score | Team | Record | Region |
| (3) | 65 | Michigan State | 26-8 | (14) | 54 | Valparaiso | 26-8 | Midwest |
| (6) | 68 | Butler | 27-8 | (11) | 56 | Bucknell | 28-6 | East |
| (8) | 55 | Pittsburgh | 24-9 | * (9) | 73 | Wichita State | 28-8 | West |
| (4) | 64 | St. Louis | 27-6 | (13) | 44 | New Mexico State | 24-11 | Midwest |
| (6) | 54 | Memphis | 31-4 | (11) | 52 | St. Mary’s | 28-7 | Midwest |
| (3) | 59 | Marquette | 24-8 | (14) | 58 | Davidson | 26 – 8 | East |
| (1) | 64 | Gonzaga | 32-2 | (16) | 58 | Southern | 23-10 | West |
| (5) | 55 | Oklahoma State | 24-9 | * (12) | 68 | Oregon | 27-8 | Midwest |
| (1) | 79 | Louisville | 30-5 | (16) | 48 | N.C. A&T | 20-17 | Midwest |
| (4) | 71 | Michigan | 27-7 | (13) | 56 | South Dakota St. | 25-10 | South |
| (6) | 81 | Arizona | 26-7 | (11) | 64 | Belmont | 26-7 | West |
| (5) | 61 | UNLV | 25-10 | * (12) | 64 | California | 21-11 | East |
| (8) | 84 | Colorado State | 26-8 | (9) | 72 | Missouri | 23-11 | Midwest |
| (5) | 88 | VCU | 27-8 | (12) | 42 | Akron | 26-7 | South |
| (3) | 62 | New Mexico | 29-6 | * (14) | 68 | Harvard | 20-9 | West |
| (4) | 81 | Syracuse | 27-9 | (13) | 34 | Montana | 25-7 | East |
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